Effect of metformin and metformin/linagliptin on gut microbiota in patients with prediabetes

Effect of metformin and metformin/linagliptin on gut microbiota in patients with prediabetes

Abstract Lifestyle modifications, metformin, and linagliptin reduce the incidence of type 2 diabetes (T2D) in people with prediabetes. The gut microbiota (GM) may enhance such interventions' efficacy. We determined the effect of linagliptin/metformin (LM) vs metformin (M) on GM composition and...

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Bibliographic Details
Main Authors: Yoscelina Estrella Martínez-López, Daniel Neri-Rosario, Diego Armando Esquivel-Hernández, Cristian Padron-Manrique, Aarón Vázquez-Jiménez, Jean Paul Sánchez-Castañeda, David Girón-Villalobos, Cristian Mendoza-Ortíz, María de Lourdes Reyes-Escogido, Maria Lola Evia-Viscarra, Alberto Aguilar-Garcia, Osbaldo Resendis-Antonio, Rodolfo Guardado-Mendoza
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Gut microbiota
Metformin
Linagliptin/metformin
Insulin resistance
Pancreatic β-cell function
Online Access:https://doi.org/10.1038/s41598-024-60081-y

Internet

https://doi.org/10.1038/s41598-024-60081-y

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