<i>PPP1R7</i> Is a Novel Translocation Partner of <i>CBFB</i> via t(2;16)(q37;q22) in Acute Myeloid Leukemia

<i>PPP1R7</i> Is a Novel Translocation Partner of <i>CBFB</i> via t(2;16)(q37;q22) in Acute Myeloid Leukemia

In a subset of acute myeloid leukemia (AML) cases, the core binding factor beta subunit gene (<i>CBFB</i>) was rearranged via inv(16)(p13.1q22) or t(16;16)(p13.1;q22), in which the smooth muscle myosin heavy chain 11 gene (<i>MYH11</i>) was the partner (<i>CBFB::MYH11&l...

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Bibliographic Details
Main Authors: Lulu Wang, Wei Wang, Hannah C. Beird, Xueqian Cheng, Hong Fang, Guilin Tang, Gokce A. Toruner, C. Cameron Yin, M. James You, Ghayas C. Issa, Gautam Borthakur, Guang Peng, Joseph D. Khoury, L. Jeffrey Medeiros, Zhenya Tang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
<i>CBFB</i> rearrangement
novel partner gene
<i>PPP1R7</i>
microhomology
AML
Online Access:https://www.mdpi.com/2073-4425/13/8/1367

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https://www.mdpi.com/2073-4425/13/8/1367

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