Improvement of sabinene tolerance of Escherichia coli using adaptive laboratory evolution and omics technologies

Improvement of sabinene tolerance of Escherichia coli using adaptive laboratory evolution and omics technologies

Abstract Background Biosynthesis of sabinene, a bicyclic monoterpene, has been accomplished in engineered microorganisms by introducing heterologous pathways and using renewable sugar as a carbon source. However, the efficiency and titers of this method are limited by the low host tolerance to sabin...

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Bibliographic Details
Main Authors: Tong Wu, Jinfeng Liu, Meijie Li, Ge Zhang, Lijuan Liu, Xing Li, Xiao Men, Mo Xian, Haibo Zhang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Biotechnology for Biofuels
Subjects:
Escherichia coli
Sabinene tolerance
Adaptive laboratory evolution
Genome resequencing
Transcriptome sequencing
ybcK/ygiZ/scpA
Online Access:http://link.springer.com/article/10.1186/s13068-020-01715-x

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http://link.springer.com/article/10.1186/s13068-020-01715-x

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