Ezrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3.

Ezrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3.

The sodium hydrogen exchanger isoform 3 (NHE3) mediates absorption of sodium, bicarbonate and water from renal and intestinal lumina. This activity is fundamental to the maintenance of a physiological plasma pH and blood pressure. To perform this function NHE3 must be present in the apical membrane...

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Bibliographic Details
Main Authors: Hisayoshi Hayashi, Atsushi Tamura, Devishree Krishnan, Sachiko Tsukita, Yuichi Suzuki, Hetal S Kocinsky, Peter S Aronson, John Orlowski, Sergio Grinstein, R Todd Alexander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3566197?pdf=render

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http://europepmc.org/articles/PMC3566197?pdf=render

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