NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis.

NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis.

AP-2 is the core-organizing element in clathrin-mediated endocytosis. During the formation of clathrin-coated vesicles, clathrin and endocytic accessory proteins interact with AP-2 in a temporally and spatially controlled manner, yet it remains elusive as to how these interactions are regulated. Her...

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Bibliographic Details
Main Authors: Brigitte Ritter, Sebastian Murphy, Hatem Dokainish, Martine Girard, Manasa V Gudheti, Guennadi Kozlov, Marilene Halin, Jacynthe Philie, Erik M Jorgensen, Kalle Gehring, Peter S McPherson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3794858?pdf=render

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http://europepmc.org/articles/PMC3794858?pdf=render

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