Hydrolysis of Oligodeoxyribonucleotides on the Microarray Surface and in Solution by Catalytic Anti-DNA Antibodies in Systemic Lupus Erythematosus

Hydrolysis of Oligodeoxyribonucleotides on the Microarray Surface and in Solution by Catalytic Anti-DNA Antibodies in Systemic Lupus Erythematosus

Anti-DNA antibodies are known to be classical serological hallmarks of systemic lupus erythematosus (SLE). In addition to high-affinity antibodies, the autoantibody pool also contains natural catalytic anti-DNA antibodies that recognize and hydrolyze DNA. However, the specificity of such antibodies...

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Bibliographic Details
Main Authors: Tatiana S. Novikova, Evgeny A. Ermakov, Elena V. Kostina, Alexander N. Sinyakov, Alexey E. Sizikov, Georgy A. Nevinsky, Valentina N. Buneva
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Current Issues in Molecular Biology
Subjects:
systemic lupus erythematosus
SLE
anti-DNA antibodies
antinuclear antibodies
natural catalytic antibodies
abzymes
Online Access:https://www.mdpi.com/1467-3045/45/12/617

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https://www.mdpi.com/1467-3045/45/12/617

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