Generation of hepatitis C virus–resistant liver cells by genome editing–mediated stable expression of RNA aptamer
Hepatitis C virus (HCV) infections frequently recur after liver transplantation in patients with HCV-related liver diseases. Approximately 30% of these patients progress to cirrhosis within 5 years after surgery. In this study, we proposed an effective therapeutic strategy to overcome the recurrence...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050123001900 |