Chemical Attachment of 5-Nitrosalicylaldimine Motif to Silatrane Resulting in an Organic–Inorganic Structure with High Medicinal Significance

Chemical Attachment of 5-Nitrosalicylaldimine Motif to Silatrane Resulting in an Organic–Inorganic Structure with High Medicinal Significance

Two chemical motifs of interest for medicinal chemistry, silatrane as 1-(3-aminopropyl) silatrane (SIL M), and nitro group attached in position 5 to salicylaldehyde, are coupled in a new structure, 1-(3-{[(2-hydroxy-5-nitrophenyl)methylidene]amino}propyl)silatrane (SIL-BS), through an azomethine moi...

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Bibliographic Details
Main Authors: Mirela-Fernanda Zaltariov, Mihaela Turtoi, Dragos Peptanariu, Ana-Maria Macsim, Lilia Clima, Corneliu Cojocaru, Nicoleta Vornicu, Bianca-Iulia Ciubotaru, Alexandra Bargan, Manuela Calin, Maria Cazacu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
1-(3-aminopropyl)silatrane
2-hydroxy-5-nitrobenzaldehyde
azomethine
protein binding
cytotoxicity
Online Access:https://www.mdpi.com/1999-4923/14/12/2838

Internet

https://www.mdpi.com/1999-4923/14/12/2838

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