Multidimensional analysis of behavior predicts genotype with high accuracy in a mouse model of Angelman syndrome
Abstract Angelman syndrome (AS) is a neurodevelopmental disorder caused by loss of expression of the maternal copy of the UBE3A gene. Individuals with AS have a multifaceted behavioral phenotype consisting of deficits in motor function, epilepsy, cognitive impairment, sleep abnormalities, as well as...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-10-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-022-02206-3 |