microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.

Animal microRNAs (miRNAs) typically regulate gene expression by binding to partially complementary target sites in the 3' untranslated region (UTR) of messenger RNA (mRNA) reducing its translation and stability. They also commonly induce shortening of the mRNA 3' poly(A) tail, which contri...

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Detaylı Bibliyografya
Asıl Yazarlar: Traude H Beilharz, David T Humphreys, Jennifer L Clancy, Rolf Thermann, David I K Martin, Matthias W Hentze, Thomas Preiss
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2009-08-01
Seri Bilgileri:PLoS ONE
Online Erişim:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19710908/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19710908/pdf/?tool=EBI

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