Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro

Abstract Background Muscle disuse results in loss of skeletal muscle mass and function. Hochu-ekki-to (TJ-41; Bu-Zhong-Yi-Qi-Tang in Chinese) is an herbal medicinal formulation used to treat patients with frailty, fatigue and appetite loss. It has been suggested that two atrogenes, atrogin-1 and mus...

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Bibliographic Details
Main Authors: Mitsutaka Yakabe, Tatsuya Hosoi, Hiroko Sasakawa, Masahiro Akishita, Sumito Ogawa
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Complementary Medicine and Therapies
Subjects:
TJ-41
Tail-suspension
atrogin-1
AMPK
Herbal medicine
Online Access:https://doi.org/10.1186/s12906-022-03812-w

Internet

https://doi.org/10.1186/s12906-022-03812-w

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