Kampo formula hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang, TJ-41) ameliorates muscle atrophy by modulating atrogenes and AMPK in vivo and in vitro
Abstract Background Muscle disuse results in loss of skeletal muscle mass and function. Hochu-ekki-to (TJ-41; Bu-Zhong-Yi-Qi-Tang in Chinese) is an herbal medicinal formulation used to treat patients with frailty, fatigue and appetite loss. It has been suggested that two atrogenes, atrogin-1 and mus...
Main Authors: | Mitsutaka Yakabe, Tatsuya Hosoi, Hiroko Sasakawa, Masahiro Akishita, Sumito Ogawa |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | BMC Complementary Medicine and Therapies |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12906-022-03812-w |
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