Major data analysis errors invalidate cancer microbiome findings

Major data analysis errors invalidate cancer microbiome findings

ABSTRACT We re-analyzed the data from a recent large-scale study that reported strong correlations between DNA signatures of microbial organisms and 33 different cancer types and that created machine-learning predictors with near-perfect accuracy at distinguishing among cancers. We found at least tw...

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Bibliographic Details
Main Authors: Abraham Gihawi, Yuchen Ge, Jennifer Lu, Daniela Puiu, Amanda Xu, Colin S. Cooper, Daniel S. Brewer, Mihaela Pertea, Steven L. Salzberg
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
microbiome
cancer
bioinformatics
computational biology
metagenomics
Online Access:https://journals.asm.org/doi/10.1128/mbio.01607-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01607-23

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