Core and shell platelets of a thrombus: A new microfluidic assay to study mechanics and biochemistry
Abstract Background Hemostatic clots have a P‐selectin positive platelet core covered with a shell of P‐selectin negative platelets. Objective To develop a new human blood microfluidic assay to interrogate core/shell mechanics. Methods A 2‐stage assay perfused whole blood over collagen/± tissue fact...
Main Authors: | Michael E. DeCortin, Lawrence F. Brass, Scott L. Diamond |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-10-01
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Series: | Research and Practice in Thrombosis and Haemostasis |
Subjects: | |
Online Access: | https://doi.org/10.1002/rth2.12405 |
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