HIV-1 adaptation to NK cell-mediated immune pressure.
The observation, by Alter et al., of the enrichment of NK cell "escape" variants in individuals carrying certain Killer-cell Immunoglobulin-like Receptor (KIR) genes is compelling evidence that natural killer (NK) cells exert selection pressure on HIV-1. Alter et al hypothesise that varian...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-06-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC5472325?pdf=render |