CRISPR-Cas9 and Cas12a target site richness reflects genomic diversity in natural populations of Anopheles gambiae and Aedes aegypti mosquitoes

CRISPR-Cas9 and Cas12a target site richness reflects genomic diversity in natural populations of Anopheles gambiae and Aedes aegypti mosquitoes

Abstract Due to limitations in conventional disease vector control strategies including the rise of insecticide resistance in natural populations of mosquitoes, genetic control strategies using CRISPR gene drive systems have been under serious consideration. The identification of CRISPR target sites...

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Bibliographic Details
Main Authors: Travis C. Collier, Yoosook Lee, Derrick K. Mathias, Víctor López Del Amo
Format: Article
Language:English
Published: BMC 2024-07-01
Series:BMC Genomics
Subjects:
CRISPR
Genome editing
Cas9
Cas12a
Mosquitoes
Malaria vector
Online Access:https://doi.org/10.1186/s12864-024-10597-4

Internet

https://doi.org/10.1186/s12864-024-10597-4

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