Implications of Oxidative Stress in Glioblastoma Multiforme Following Treatment with Purine Derivatives

Implications of Oxidative Stress in Glioblastoma Multiforme Following Treatment with Purine Derivatives

Recently, small compound-based therapies have provided new insights into the treatment of glioblastoma multiforme (GBM) by inducing oxidative impairment. Kinetin riboside (KR) and newly designed derivatives (8-azaKR, 7-deazaKR) selectively affect the molecular pathways crucial for cell growth by int...

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Bibliographic Details
Main Authors: Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Dorota Gurda-Woźna, Paweł Pawelczak, Patrycja Krawczyk, Małgorzata Giel-Pietraszuk, Grzegorz Framski, Tomasz Ostrowski, Eliza Wyszko
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Antioxidants
Subjects:
purine derivatives
kinetin riboside
glioblastoma multiforme
oxidative therapy
ROS
oxidative imbalance
Online Access:https://www.mdpi.com/2076-3921/10/6/950

Internet

https://www.mdpi.com/2076-3921/10/6/950

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