Intrinsic Bio-Signature of Gene Delivery Nanocarriers May Impair Gene Therapy Goals

Non-viral lipid/polymeric vectors have widely been used as nanocarriers (NCs) for gene delivery. They possess large surface area to volume ratio and are able to interact with biomolecules through functional moieties, resulting in inadvertent biological impacts, in particular at genomic level. Thus,...

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Bibliographic Details
Main Authors: Jaleh Barar, Yadollah Omidi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2013-09-01
Series:BioImpacts
Subjects:
Online Access:http://dx.doi.org/10.5681/bi.2013.028