Intrinsic Bio-Signature of Gene Delivery Nanocarriers May Impair Gene Therapy Goals
Non-viral lipid/polymeric vectors have widely been used as nanocarriers (NCs) for gene delivery. They possess large surface area to volume ratio and are able to interact with biomolecules through functional moieties, resulting in inadvertent biological impacts, in particular at genomic level. Thus,...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2013-09-01
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Series: | BioImpacts |
Subjects: | |
Online Access: | http://dx.doi.org/10.5681/bi.2013.028 |