Synthesis and antifungal activity investigation of a novel clotrimazole derivative
<p>Azole antifungal agents disrupt fungal ergosterol synthesis that is essential for the formation of fungal cell membrane by preventing 14-α-demethylase enzyme from binding to its substrate. Clotrimazole is one of the first generations of azole antifungal agents. To discover a novel azole ant...
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| Format: | Article |
| Language: | English |
| Published: |
Mongolian Academy of Sciences
2014-10-01
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| Series: | Mongolian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.mongoliajol.info/index.php/MJC/article/view/194 |