Apoptosis Sensitization by Euphorbia Factor L1 in ABCB1-Mediated Multidrug Resistant K562/ADR Cells

In this article, reversal activities of Euphorbia factor L1 (EFL1) against ABCB1-mediated multidrug resistance (MDR) and apoptosis sensitization in K562/ADR cells are reported. EFL1 decreased the IC50 values of anticancer agents in K562/ADR cells over-expressing ABCB1. However, EFL1 did not affect t...

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Bibliographic Details
Main Authors: Zhong-Zhen Zhao, Hu-Biao Chen, Lan-Lan Fan, Xi-Cheng He, Yi-Na Tang, Tao Yi, Jian-Ye Zhang, Min-Ting Lin
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/10/12793