Descriptors of Secondary Active Transporter Function and How They Relate to Partial Reactions in the Transport Cycle

Descriptors of Secondary Active Transporter Function and How They Relate to Partial Reactions in the Transport Cycle

Plasmalemmal solute carriers (SLC<i>s</i>) gauge and control solute abundance across cellular membranes. By virtue of this action, they play an important role in numerous physiological processes. Mutations in genes encoding the SLCs alter amino acid sequence that often leads to impaired...

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Bibliographic Details
Main Authors: Klaus Schicker, Shreyas Bhat, Clemens Farr, Verena Burtscher, Andreas Horner, Michael Freissmuth, Walter Sandtner
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Membranes
Subjects:
secondary active transporters
solute carrier proteins
monogenetic disorders
descriptors of transport function
kinetic model
Online Access:https://www.mdpi.com/2077-0375/11/3/178

Internet

https://www.mdpi.com/2077-0375/11/3/178

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