38766 Massively Parallel Reporter Assay Reveals Functional Impact of 3™-UTR SNPs Associated with Neurological and Psychiatric Disorders

ABSTRACT IMPACT: Screening the effect of thousands of non-coding genetic variants will help identify variants important in the etiology of diseases OBJECTIVES/GOALS: Massively parallel reporter assays (MPRAs) can experimentally evaluate the impact of genetic variants on gene expression. In this stud...

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Bibliographic Details
Main Authors: Andy B. Chen, Kriti Thapa, Hongyu Gao, Jill L. Reiter, Junjie Zhang, Xiaoling Xuei, Hongmei Gu, Yue Wang, Howard J. Edenberg, Yunlong Liu
Format: Article
Language:English
Published: Cambridge University Press 2021-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866121006452/type/journal_article