Synergy effects of copper ion in doxorubicin-based chelate prodrug for cancer chemo-chemodynamic combination therapy
AbstractDoxorubicin (DOX) is a commonly studied chemotherapeutic agent for the treatment of solid tumors, but the severe side effects limit its clinical application. It is shown that DOX-metal chelate has lower in vitro cytotoxicity compared with DOX, as the anthracyclines of DOX can form coordinati...
| Main Authors: | , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
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Taylor & Francis Group
2023-12-01
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| 丛编: | Drug Delivery |
| 主题: | |
| 在线阅读: | https://www.tandfonline.com/doi/10.1080/10717544.2023.2219426 |