KF-1 ubiquitin ligase: an anxiety suppressor

Anxiety is an instinct that may have developed to promote adaptive survival by evading unnecessary danger. However, excessive anxiety is disruptive and can be a basic disorder of other psychiatric diseases such as depression. The KF-1, a ubiquitin ligase located to the endoplasmic reticulum (ER), ma...

Full description

Bibliographic Details
Main Authors: Tamotsu Hashimoto-Gotoh, Naoyuki Iwabe, Atsushi Tsujimura, Keizo Takao, Tsuyoshi Miyakawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-05-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.01.004.2009/full