Identifying Potential Molecular Targets in Fungi Based on (Dis)Similarities in Binding Site Architecture with Proteins of the Human Pharmacolome

Identifying Potential Molecular Targets in Fungi Based on (Dis)Similarities in Binding Site Architecture with Proteins of the Human Pharmacolome

Invasive fungal infections represent a public health problem that worsens over the years with the increasing resistance to current antimycotic agents. Therefore, there is a compelling medical need of widening the antifungal drug repertoire, following different methods such as drug repositioning, ide...

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Bibliographic Details
Main Authors: Johann E. Bedoya-Cardona, Marcela Rubio-Carrasquilla, Iliana M. Ramírez-Velásquez, Mario S. Valdés-Tresanco, Ernesto Moreno
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
fungal pathogens
drug repurposing
drug development
new therapeutic targets
structural bioinformatics
MEK inhibitors
Online Access:https://www.mdpi.com/1420-3049/28/2/692

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https://www.mdpi.com/1420-3049/28/2/692

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