Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

Summary Neural stem and progenitor cell (NSPC) transplants provide neuroprotection in models of acute brain injury, but the underlying mechanisms are not fully understood. Here, we provide evidence that caspase-dependent apoptotic cell death of NSPCs is required for sending survival signals to the i...

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Bibliographic Details
Main Authors: Wei Han, Eva-Maria Meißner, Stefanie Neunteibl, Madeline Günther, Jörg Kahnt, Amalia Dolga, Cuicui Xie, Nikolaus Plesnila, Changlian Zhu, Klas Blomgren, Carsten Culmsee
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05698-z

Internet

https://doi.org/10.1038/s41419-023-05698-z

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