Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) remains the most common cause of liver disease in the United States due to the increased incidence of metabolic dysfunction and obesity. Surfactant protein A (SPA) regulates macrophage function, strongly binds to lipids, and i...

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Bibliographic Details
Main Authors: Ayobami Dare, Skylar D. King, Shi-You Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58291-5