Barriers to transmission of transcriptional noise in a c‐fos c‐jun pathway

We explored how transcriptional noise propagates in gene‐regulatory pathways by studying the induction of two downstream genes by transcription factors c‐fos and c‐jun. They are produced for a brief period following serum stimulation of cells and then activate the promoters of their target genes by...

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Bibliographic Details
Main Authors: Khyati Shah, Sanjay Tyagi
Format: Article
Language:English
Published: Springer Nature 2013-01-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2013.45