Comprehensive Genomic Profiling of Circulating Cell-Free DNA Distinguishes Focal <i>MET</i> Amplification from Aneuploidy in Diverse Advanced Cancers

Comprehensive Genomic Profiling of Circulating Cell-Free DNA Distinguishes Focal <i>MET</i> Amplification from Aneuploidy in Diverse Advanced Cancers

Amplification (amp) of <i>MET</i> can be observed in cases of focal gene copy number gain, such as <i>MET</i>-driven amp, or with a gain of chromosome 7, such as aneuploidy. Several studies have shown that only high-level focal <i>MET</i> amp (<i>MET</i&g...

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Bibliographic Details
Main Authors: Yuichi Kumaki, Steve Olsen, Mitsukuni Suenaga, Tsuyoshi Nakagawa, Hiroyuki Uetake, Sadakatsu Ikeda
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Current Oncology
Subjects:
<i>MET</i>
ctDNA
cfDNA
liquid biopsies
focal amplification
aneuploidy
Online Access:https://www.mdpi.com/1718-7729/28/5/317

Internet

https://www.mdpi.com/1718-7729/28/5/317

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