Investigation of Methyl-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxyhydrazide Derivatives as Potential Inhibitors of COVID-19 Main Protease: DFT and Molecular Docking Study

Investigation of Methyl-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxyhydrazide Derivatives as Potential Inhibitors of COVID-19 Main Protease: DFT and Molecular Docking Study

The search for effective therapeutics to combat COVID-19 has led to the exploration of the biological activity of numerous compounds. In this study, hydrazones derived from oseltamivir intermediate, methyl 5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate have been investigated for thei...

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Bibliographic Details
Main Authors: Olawale Folorunso Akinyele, Emmanuel Gabriel Fakola, Omolara Olubunmi Adeboye, Sunday Chimela Chinuomah
Format: Article
Language:English
Published: SAGE Publishing 2023-06-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.1177/11779322231182050

Internet

https://doi.org/10.1177/11779322231182050

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