Meta Analysis of Human AlzGene Database: Benefits and Limitations of Using C. elegans for the Study of Alzheimer's Disease and Co-morbid Conditions

Meta Analysis of Human AlzGene Database: Benefits and Limitations of Using C. elegans for the Study of Alzheimer's Disease and Co-morbid Conditions

Human genome-wide association studies (GWAS) and linkage studies have identified 695 genes associated with Alzheimer's disease (AD), the vast majority of which are associated with late-onset AD. Although orthologs of these AD genes have been studied in several model species, orthologs in the ne...

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Bibliographic Details
Main Authors: Behrad Vahdati Nia, Christine Kang, Michelle G. Tran, Deborah Lee, Shin Murakami
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Genetics
Subjects:
Alzheimer's disease (AD)
amyotrophic lateral sclerosis (ALS)
comorbidity
genome-wide association study (GWAS)
meta-analysis
multiple sclerosis (MS)
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00055/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2017.00055/full

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