Polymer lipid hybrid nanoparticles encapsulated with Emodin combined with DOX reverse multidrug resistance of breast cancer via IL-6/JAK2/STAT3 signaling pathway

Polymer lipid hybrid nanoparticles encapsulated with Emodin combined with DOX reverse multidrug resistance of breast cancer via IL-6/JAK2/STAT3 signaling pathway

Abstract Multidrug resistance (MDR) is one of the main reasons affecting the efficacy of chemotherapy in breast cancer (BC). Our previous studies constructed polymer lipid hybrid nanoparticles encapsulated with Emodin (EMO) (E-PLNs) and proved that they can inhibit epithelial mesenchymal transition...

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Bibliographic Details
Main Authors: Honghui Gu, Fansu Meng, Haidong Sun, Lina Yang, Qi Li, Zhong Chen, Tiange Cai, Zhenjiang Yang, Yu Cai
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cancer Nanotechnology
Subjects:
Breast cancer
Multidrug resistance
Nanoparticles
Emodin
Epithelial mesenchymal transition
Online Access:https://doi.org/10.1186/s12645-023-00237-z

Internet

https://doi.org/10.1186/s12645-023-00237-z

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