Mitochondrial Dysfunction in Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder caused by recessive mutations in the <i>SMN1</i> gene, globally affecting ~8–14 newborns per 100,000. The severity of the disease depends on the residual levels of functional survival of motor neuron protein, SMN. SMN...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-09-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/18/10878 |