MAPK4 silencing in gastric cancer drives liver metastasis by positive feedback between cancer cells and macrophages

MAPK4 silencing in gastric cancer drives liver metastasis by positive feedback between cancer cells and macrophages

Gastric cancer: Gene shutdown helps spread to the liver Reduced activity of a key cell control gene mediates an interaction between gastric cancer cells and immune system cells called macrophages that allows the cancer to spread to the liver. Cancer cells migrating to the liver is a major cause of d...

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Bibliographic Details
Main Authors: Shuang Li, Dongyang Guo, Qiang Sun, Lu Zhang, Yun Cui, Min Liu, Xixi Ma, Yiman Liu, Wenyu Cui, Leimin Sun, Lisong Teng, Liangjing Wang, Aifu Lin, Wei Liu, Wei Zhuo, Tianhua Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00946-w

Internet

https://doi.org/10.1038/s12276-023-00946-w

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