Overexpression of hypoxia-inducible factor 1 alpha improves immunomodulation by dental mesenchymal stem cells

Overexpression of hypoxia-inducible factor 1 alpha improves immunomodulation by dental mesenchymal stem cells

Abstract Background Human dental mesenchymal stem cells (MSCs) are considered as highly accessible and attractive MSCs for use in regenerative medicine, yet some of their features are not as well characterized as other MSCs. Hypoxia-preconditioning and hypoxia-inducible factor 1 (HIF-1) alpha overex...

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Bibliographic Details
Main Authors: Victor G. Martinez, Imelda Ontoria-Oviedo, Carolina P. Ricardo, Sian E. Harding, Rosa Sacedon, Alberto Varas, Agustin Zapata, Pilar Sepulveda, Angeles Vicente
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells (MSCs)
Hypoxia-inducible factor 1 alpha subunit (HIF-1 alpha)
Immunomodulation
Cell therapy
Dental pulp
Online Access:http://link.springer.com/article/10.1186/s13287-017-0659-2

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http://link.springer.com/article/10.1186/s13287-017-0659-2

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