Loss of function mutations in essential genes cause embryonic lethality in pigs.

Loss of function mutations in essential genes cause embryonic lethality in pigs.

Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals, reducing fertility. Especially in small size domestic and wild populations, those alleles might be exposed by inbreeding, caused by matings between related parents that inherited the same recessive lethal alle...

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Bibliographic Details
Main Authors: Martijn F L Derks, Arne B Gjuvsland, Mirte Bosse, Marcos S Lopes, Maren van Son, Barbara Harlizius, Beatrice F Tan, Hanne Hamland, Eli Grindflek, Martien A M Groenen, Hendrik-Jan Megens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6436757?pdf=render

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http://europepmc.org/articles/PMC6436757?pdf=render

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