Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegans

Systematic characterization of chromodomain proteins reveals an H3K9me1/2 reader regulating aging in C. elegans

Chromodomains mainly function as histone methyl-lysine readers to regulate gene expression. Here the authors delineate a functional map of chromodomain proteins and identify an H3K9me1/2 writer, MET-2, and reader, CEC-5, that are required for the normal lifespan of C. elegans.

Bibliographic Details
Main Authors: Xinhao Hou, Mingjing Xu, Chengming Zhu, Jianing Gao, Meili Li, Xiangyang Chen, Cheng Sun, Björn Nashan, Jianye Zang, Ying Zhou, Shouhong Guang, Xuezhu Feng
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36898-y

Internet

https://doi.org/10.1038/s41467-023-36898-y

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