Complex effects of kinase localization revealed by compartment-specific regulation of protein kinase A activity

Kinase activity in signaling networks frequently depends on regulatory subunits that can both inhibit activity by interacting with the catalytic subunits and target the kinase to distinct molecular partners and subcellular compartments. Here, using a new synthetic molecular interaction system, we sh...

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Bibliographic Details
Main Authors: Rebecca LaCroix, Benjamin Lin, Tae-Yun Kang, Andre Levchenko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/66869