C. elegans as an in vivo model system for the phenotypic drug discovery for treating paraquat poisoning

Background Paraquat (PQ) is an effective and widely used herbicide and causes numerous fatalities by accidental or voluntary ingestion. However, neither the final cytotoxic mechanism nor effective treatments for PQ poisoning have been discovered. Phenotypic drug discovery (PDD), which does not rely...

Full description

Bibliographic Details
Main Authors: Peng Ji, Hongyuan Li, Yushan Jin, Yinghua Peng, Lihui Zhao, Xiaohui Wang
Format: Article
Language:English
Published: PeerJ Inc. 2022-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12866.pdf