Generation of rat offspring using spermatids produced through in vitro spermatogenesis

Abstract An in vitro spermatogenesis method using mouse testicular tissue to produce fertile sperm was established more than a decade ago. Although this culture method has generally not been effective in other animal species, we recently succeeded in improving the culture condition to induce spermat...

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Bibliographic Details
Main Authors: Takafumi Matsumura, Kumiko Katagiri, Tatsuma Yao, Yu Ishikawa-Yamauchi, Shino Nagata, Kiyoshi Hashimoto, Takuya Sato, Hiroshi Kimura, Takashi Shinohara, Makoto Sanbo, Masumi Hirabayashi, Takehiko Ogawa
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39304-1