Counteracting protein kinase activity in the heart: The multiple roles of protein phosphatases

Decades of cardiovascular research have shown that variable and flexible levels of protein phosphorylation are necessary to maintain cardiac function. A delicate balance between phosphorylated and dephosphorylated states of proteins is guaranteed by a complex interplay of protein kinases (PK) and ph...

Full description

Bibliographic Details
Main Authors: Silvio eWeber, Stefanie eMeyer-Roxlau, Michael eWagner, Dobromir eDobrev, Ali eEl-Armouche
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00270/full