Indirect Mechanisms of Transcription Factor‐Mediated Gene Regulation during Cell Fate Changes

Indirect Mechanisms of Transcription Factor‐Mediated Gene Regulation during Cell Fate Changes

Abstract Transcription factors (TFs) are the master regulators of cellular identity, capable of driving cell fate transitions including differentiations, reprogramming, and transdifferentiations. Pioneer TFs recognize partial motifs exposed on nucleosomal DNA, allowing for TF‐mediated activation of...

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Bibliographic Details
Main Authors: Michael R. Larcombe, Sheng Hsu, Jose M. Polo, Anja S. Knaupp
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Advanced Genetics
Subjects:
cellular reprogramming
decoy DNA
iPSCs
pluripotency
sponge effect
transcription factor
Online Access:https://doi.org/10.1002/ggn2.202200015

Internet

https://doi.org/10.1002/ggn2.202200015

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