Indirect Mechanisms of Transcription Factor‐Mediated Gene Regulation during Cell Fate Changes
Abstract Transcription factors (TFs) are the master regulators of cellular identity, capable of driving cell fate transitions including differentiations, reprogramming, and transdifferentiations. Pioneer TFs recognize partial motifs exposed on nucleosomal DNA, allowing for TF‐mediated activation of...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-12-01
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Series: | Advanced Genetics |
Subjects: | |
Online Access: | https://doi.org/10.1002/ggn2.202200015 |