Induction of Apoptosis by Sinulariolide from Soft Coral through Mitochondrial-Related and p38MAPK Pathways on Human Bladder Carcinoma Cells

Sinulariolide, an isolated compound from the soft coral Sinularia flexibilis, possesses the anti-proliferative, anti-migratory and apoptosis-inducing activities against the TSGH bladder carcinoma cell. The anti-tumor effects of sinulariolide were determined by 3-(4,5-cimethylthiazol-2-yl)-2,5-diphen...

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Bibliographic Details
Main Authors: Jui-Hsin Su, Yu-Kuei Chen, Feng-Jen Tsai, Yu-Jen Wu, Shun-Hsiang Weng, Zhong-Hao Din, Choo-Aun Neoh, Robert Y.-L. Wang
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/10/12/2893