IFN-γ Critically Enables the Intratumoural Infiltration of CXCR3<sup>+</sup> CD8<sup>+</sup> T Cells to Drive Squamous Cell Carcinoma Regression
Ultraviolet (UV) radiation-induced tumours carry a high mutational load, are highly immunogenic, and often fail to grow when transplanted into normal, syngeneic mice. The aim of this study was to investigate factors critical for the immune-mediated rejection of cutaneous squamous cell carcinoma (SCC...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/9/2131 |