Activation of Slit2/Robo1 Signaling Promotes Tumor Metastasis in Colorectal Carcinoma through Activation of the TGF-β/Smads Pathway
Slit2 (slit guidance ligand 2), a ligand of the Roundabout1 (Robo1) transmembrane receptor, is often overexpressed in colorectal carcinomas (CRCs). In this study, we performed data mining in the Metabolic gEne RApid Visualizer (MERAV) database and found that Slit2 and TGF-β1 (Transforming g...
Main Authors: | Yuying Yao, Zijun Zhou, Liuyou Li, Junchen Li, Lixun Huang, Jiangchao Li, Cuiling Qi, Lingyun Zheng, Lijing Wang, Qian-Qian Zhang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-06-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/6/635 |
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