The molecular mechanism and challenge of targeting XPO1 in treatment of relapsed and refractory myeloma
Multiple myeloma (MM) treatment regimens have vastly improved since the introduction of immunomodulators, proteasome inhibitors, and anti-CD38 monoclonal antibodies; however, MM is considered an incurable disease due to inevitable relapse and acquired drug resistance. Understanding the molecular mec...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-08-01
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Series: | Translational Oncology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523322001073 |