A Potential Nutraceutical Candidate Lactucin Inhibits Adipogenesis through Downregulation of JAK2/STAT3 Signaling Pathway-Mediated Mitotic Clonal Expansion

A Potential Nutraceutical Candidate Lactucin Inhibits Adipogenesis through Downregulation of JAK2/STAT3 Signaling Pathway-Mediated Mitotic Clonal Expansion

The prevalence of obesity has increased dramatically worldwide in the past ~50 years. Searching for safe and effective anti-obesity strategies are urgently needed. Lactucin, a plant-derived natural small molecule, is known for anti-malaria and anti-hyperalgesia. The study is to investigate whether l...

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Bibliographic Details
Main Authors: Xin Wang, Min Liu, Guo He Cai, Yan Chen, Xiao Chen Shi, Cong Cong Zhang, Bo Xia, Bao Cai Xie, Huan Liu, Rui Xin Zhang, Jun Feng Lu, Meng Qing Zhu, Shi Zhen Yang, Xin Yi Chu, Dan Yang Zhang, Yong Liang Wang, Jiang Wei Wu
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
lactucin
adipogenesis
jak2/stat3
mitotic clonal expansion (mce)
adipocyte
obesity
Online Access:https://www.mdpi.com/2073-4409/9/2/331

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https://www.mdpi.com/2073-4409/9/2/331

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