Altered recruitment of Sp isoforms to HIV-1 long terminal repeat between differentiated monoblastic cell lines and primary monocyte-derived macrophages

Altered recruitment of Sp isoforms to HIV-1 long terminal repeat between differentiated monoblastic cell lines and primary monocyte-derived macrophages

Human immunodeficiency virus type 1 (HIV-1) transcription in cells of the monocyte-macrophage lineage is regulated by interactions between the HIV-1 long terminal repeat (LTR) and a variety of host cell and viral proteins. Binding of the Sp family of transcription factors (TFs) to the G/C box array...

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Bibliographic Details
Main Authors: John J. McAllister, Satinder Dahiya, Rachel Berman, Mackenzie Collins, Michael R. Nonnemacher, Tricia H. Burdo, Brian Wigdahl
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Virology
Subjects:
HIV-1 LTR
Sp
G/C box array
transcription
monocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.971293/full

Internet

https://www.frontiersin.org/articles/10.3389/fviro.2022.971293/full

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