MONITORING AMPHOTERICIN B AND FLUCONAZOLE CONCENTRATIONS IN THE PLASMA AND CEREBROSPINAL FLUID OF PATIENTS WITH CRYPTOCOCCAL MENINGITIS

MONITORING AMPHOTERICIN B AND FLUCONAZOLE CONCENTRATIONS IN THE PLASMA AND CEREBROSPINAL FLUID OF PATIENTS WITH CRYPTOCOCCAL MENINGITIS

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Objetivos: Através de estudo comparativo em pacientes HIV positivo com meningite criptocócica, investigar se a anfotericina B (AmB) e o fluconazol atravessam a barreira hematoencefálica de forma semelhante, com base na razão entre a concentração dos fármacos no líquor e no plasma. Métodos: Vinte e...

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Bibliographic Details
Main Authors: Sílvia Regina Cavani Jorge Santos, Mara Cristina Silva Martins Pappalardo, Grazziela Samantha Perez, Cristina Sanches-Giraud, Márcia Souza Carvalho Melhem
Format: Article
Language:English
Published: Formifarma, LDA. 2012-12-01
Series:Revista Portuguesa de Farmacoterapia
Subjects:
Anfotericina B
Fluconazol
razão líquor/plasma
pacientes HIV e meningite criptocócica
Online Access:http://farmacoterapia.pt/index.php/rpf/article/view/61

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http://farmacoterapia.pt/index.php/rpf/article/view/61

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